Protein Expression Analysis by Signature Peptides Using Microfluidic 21) Separation Devices
نویسندگان
چکیده
We are developing methods for analyzing complex protein mixtures via the use of signature peptides that can be rapidly separated using microfluidic devices. Computer analysis of human and E. coli protein databases has shown that a high percentage of proteins have unique Cand N-terminal peptide sequences, that can potentially be used for unambiguous identification and quantitation of the parent proteins. A method of isolating N-terminal peptides for this purpose has been demonstrated.
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تاریخ انتشار 2003